Hello,

I use SCCM2012R2 on one server (site server, distribution point, Endpoint protection, OSD, SUS, SQL Server 2012 w/SP1)

Is possible in-place upgrade OS from Windows 2012 Server to Windows 2012 R2 Server ?

Thanks,

Snake AG

Yes, that it supported http://technet.microsoft.com/en-us/library/gg682077.aspx#BKMK_UpgradeInfrastructure

"Inplace upgrade from Windows Server 2012 to Windows Server 2012 R2."

Make sure you initialize your WSUS instance as that a whole new version of WSUS also. ALso, I would perform a site reset.

Here's a post I did a while back on this: http://blog.configmgrftw.com/configmgr-os-upgrades/