I have 2 domains added to exchange. the primary domain allows me to send and receive. The second domain receives e-mails fine but everytime I try to reply back to the messages received it gives me this error.You do not have permission to send to this recipient. For assistance, contact your system administrator.Thanks

Hi Njohn, Just to clear up confusion, I take it you are talking about multiple ad domains in the same forest pointing to the same exchange organisationand not smtp domains? Can you provide a bit more information on how your enviroment is configured, what e-mails addresses are going where (use example domains like abc.com), who's reply to what (internal\external recipient and whether send as is beng used) etc? Thanks, Mark