Hi All When i try to send e-mail to a specified mailbox, we are getting the below error. Bu we can sometimes send e-mail succesfully There's a problem with the recipient's mailbox. Please try resending the message. If the problem continues, please contact your helpdesk. Diagnostic information for administrators: Generating server: exchange 2010 server user@emailadreess.com Received: from Server name ([10.0.0.202]) by server name ([10.0.0.202]) with mapi; Tue, 2 Aug 2011 13:35:19 +0300 Content-Type: application/ms-tnef; name="winmail.dat" Content-Transfer-Encoding: binary From: Sender < Reporting-MTA: dns; abs.server.name Final-recipient: RFC822; user@email.com #550 5.2.0 STOREDRV.Deliver: The Microsoft Exchange Information Store service reported an error. The following information should help identify the cause of this error: "MapiExceptionCallFailed:16.18969:A1000000, 17.27161:000000005B02000000000000BD3A000000000000, 255.23226:00000000, 255.27962:05000000, 255.27962:12000000, 255.27962:13000000, 255.27962:18000000, 255.27962:4F000000, 255.17082:80040000, 0.23649:00000000, 4.21921:80040000, 255.27962:FA000000, 255.1494:13800000, 255.1238:4F000000, 6.21970:0F01048040008F660F010480, 6.21970:0F01048040008F660F010480, 6.21970:0F01048040008F660F010480, 6.21970:0F01048040008F660F010480, 6.21970:0F01048040008F660F010480, 6.21970:0F01048040008F660F010480, 6.21970:0F01048040008F660F010480, 6.21970:0F01048040008F660F010480, 6.21970:0F01048040008F660F010480, 6.21970:0F01048040008F660F010480, 0.49363:0F010480, 0.56965:0F010480, 4.45069:80040000, 4.10853:80040000, 0.65003:0F010480, 4.12901:80040000, 0.36425:0F010480, 4.11621:80040000, 4.56781:80040000, 0.21484:17010480, 4.23788:80040000, 255.1750:2D000000, 0.26849:0F010480, 255.21817:80040000, 0.29726:00000000, 4.18462:80040000". ## Original message headers: xxx@xx.com > To: =?utf-8?B?xLBseWFzIEthcmFrYXM=?= <problem@email.com > Subject: Fwd: TRT Tender for 12 x IRD SQ47174 Thread-Topic: TRT Tender for 12 x IRD SQ47174 Thread-Index: Acw8tjoveeVTEw2dQpyZGJVLOSOh5g== Date: Tue, 2 Aug 2011 13:32:26 +0300 Message-ID: < 9385C83D-8660-4F31-B16B-0FF1FD89E77A@sr > References: < 13FA43FC5837C64080AEAFAA800A2B36D4A27D91@SVr > Accept-Language: en-US Content-Language: X-MS-Has-Attach: X-MS-TNEF-Correlator: < 9385C83D-8660-4F31-B16B-0FF1FD89E77A@svstelekom.com.tr > MIME-Version: 1.0 Action: failed Status: 5.2.0 X-Supplementary-Info: < #5.2.0 smtp;550 5.2.0 STOREDRV.Deliver: The Microsoft Exchange Information Store service reported an error. The following information should help identify the cause of this error: "MapiExceptionCallFailed:16.18969:A1000000, 17.27161:000000005B02000000000000BD3A000000000000, 255.23226:00000000, 255.27962:05000000, 255.27962:12000000, 255.27962:13000000, 255.27962:18000000, 255.27962:4F000000, 255.17082:80040000, 0.23649:00000000, 4.21921:80040000, 255.27962:FA000000, 255.1494:13800000, 255.1238:4F000000, 6.21970:0F01048040008F660F010480, 6.21970:0F01048040008F660F010480, 6.21970:0F01048040008F660F010480, 6.21970:0F01048040008F660F010480, 6.21970:0F01048040008F660F010480, 6.21970:0F01048040008F660F010480, 6.21970:0F01048040008F660F010480, 6.21970:0F01048040008F660F010480, 6.21970:0F01048040008F660F010480, 6.21970:0F01048040008F660F010480, 0.49363:0F010480, 0.56965:0F010480, 4.45069:80040000, 4.10853:80040000, 0.65003:0F010480, 4.12901:80040000, 0.36425:0F010480, 4.11621:80040 000, 4.56781:80040000, 0.21484:17010480, 4.23788:80040000, 255.1750:2D000000, 0.26849:0F010480, 255.21817:80040000, 0.29726:00000000, 4.18462:80040000".> X-Display-Name: =?iso-8859-3?Q?=Username=

Only for particular domain or all domain. only for one user at particular domain or some of the users. r they sending with any attachments. If only for particular domain.ask that domain administrator to add your domain to their whitelist. -bpara

Try sending via OWA and test. Delete any autocomplete/cache and test. Create a new MAPI profile and test. If you have an attachement or an embedded image then remove and test. Sukh

Hello, Agree with Sukh. We need to first narrow down the causes. If the issue still persists when sending and receiving the emails via OWA, the issue may be related to the mailbox. Try moving the problematic mailbox to another mailbox store and see if the issue is resolved. Thanks, Simon