Hi there, First, Autodiscover service could not be disable in CAS server. It is by design. What we can do is stop Outlook from looking for Atodiscover service or, make the autodiscover service url unavailable. Regarding the cdlets, yes it should be run in EMS; after running this cmdlets, the internal url of Autodiscover service will not be available for ALL Domain users. So, if you still have Exchange users whose mailbox resided in your internal Exchange server, they will be affected. Fiona Liao TechNet Community Support