There several postings out there regarding IPV6 but nothing clear yet. Here is my question: We are deploying Exchange 2010 With SP1 on windows 2008 R2/SP1 in an environment where there is still Exchange 2003 and 2007 while migration is in proces. 1- Can we get away with disabling IPV6 on the windows 2008 box where exchange will be hosted without any issues? 2- can we disable it before installing exchange 2010 bits or shoulr we wait till the insatll is complete of all roles, including DAG? 3- If we leave IPv6 enabled. How will that affect DAG replication? PS. Right now our network is only utilizing IPV4.

It is only supported to disable IPv6 on an Exchange server if you do it via the registry key. Unchecking the IPv6 box on a network adapter has been known to cause some issues. Understanding IPv6 Support in Exchange 2010: Exchange 2010 SP1 Help fom the above link: Disable IPv6 Depending on your specific deployment, you may want to disable IPv6 on your Exchange servers. For example, because the Unified Messaging server role doesn't support IPv6, you may choose to disable IPv6 on those servers. To help you do this, use the instructions in IPv6 for Microsoft Windows: Frequently Asked Questions. You can also use these instructions to enable IPv6 if needed. Mike Crowley Check out My Blog!

Thanks. That the how. Would we need it for anything at the momemnt if our network is IPV4 based? Would disabling it cause anything?

The general response to these types of questions is: It shouldn't hurt anything if you leave it on. It also may help if you implement IPv6 in the future. But it also does not hurt anything to turn it off (if you do it properly) Mike Crowley Check out My Blog!

Thanks. Eventually we all will be heading down the IPV6 road. Just not at this time for us.