Hi Ivymdeal,
Could you tell me where did you open the file? From network or from local computer? How big is this file? Did you get any error messages when the issue appeared?
First I suggest you try to open the file in safe mode and check if this issue still exists. If it works fine please check the add-ins and disable them.
Then when this issue appeared again, open Event Viewer to check whether there's any error about the Excel crash issue. If you get any event log messages about this issue, please post the whole the whole error messages here.
According to your event log messages I can get more information of this problem. Im glad to help and follow up your reply.
Regards,
Emi Zhang
TechNet Community Su