I am running Exchagne 2003 Std SP2. One of the Admin no longer has access to all mailboxes. Nothing has changes and i have even removed the admin's righst with the Delegation wizard and added back, but still no access to the 2003 enviroment. No other admin have this issues.

Having access to the mailboxes is different than access to the Exchange Mgmt tools. See: How to assign service account access to all mailboxes in Exchange Server 2003

Thanks A_D, been a while since have setup security. The admin in question had been denied "recieve as" and 'send as" permissions.