I'm getting this error in my event viewer after mistakenly changing a binding to a SSL Cert in IIS.

A fatal alert was received from the remote endpoint. The TLS protocol defined fatal alert code is 46.

This was the error after changing the binding:  SSL Certificate Settings created by an admin process for endpoint : 0.0.0.0:443 .

Here is my CMD output for Certs:

C:\Users\Administrator.BITSERVER>netsh http show sslcert

SSL Certificate bindings:
-------------------------

    IP:port                      : 0.0.0.0:443
    Certificate Hash             : a733e531fa54b8c42e41b0584fa7e78178fdc7b0
    Application ID               : {4dc3e181-e14b-4a21-b022-59fc669b0914}
    Certificate Store Name       : My
    Verify Client Certificate Revocation : Enabled
    Verify Revocation Using Cached Client Certificate Only : Disabled
    Usage Check                  : Enabled
    Revocation Freshness Time    : 0
    URL Retrieval Timeout        : 0
    Ctl Identifier               : (null)
    Ctl Store Name               : (null)
    DS Mapper Usage              : Disabled
    Negotiate Client Certificate : Disabled

    IP:port                      : 0.0.0.0:444
    Certificate Hash             : 7e14d9733992be1fae2fe059a1098966d5ebf5b9
    Application ID               : {4dc3e181-e14b-4a21-b022-59fc669b0914}
    Certificate Store Name       : (null)
    Verify Client Certificate Revocation : Enabled
    Verify Revocation Using Cached Client Certificate Only : Disabled
    Usage Check                  : Enabled
    Revocation Freshness Time    : 0
    URL Retrieval Timeout        : 0
    Ctl Identifier               : (null)
    Ctl Store Name               : (null)
    DS Mapper Usage              : Disabled
    Negotiate Client Certificate : Disabled

    IP:port                      : 0.0.0.0:8172
    Certificate Hash             : d09cc91fa5fb43934eee8bb488211d9b04c10b88
    Application ID               : {00000000-0000-0000-0000-000000000000}
    Certificate Store Name       : MY
    Verify Client Certificate Revocation : Enabled
    Verify Revocation Using Cached Client Certificate Only : Disabled
    Usage Check                  : Enabled
    Revocation Freshness Time    : 0
    URL Retrieval Timeout        : 0
    Ctl Identifier               : (null)
    Ctl Store Name               : (null)
    DS Mapper Usage              : Disabled
    Negotiate Client Certificate : Disabled

    IP:port                      : 127.0.0.1:443
    Certificate Hash             : 7e14d9733992be1fae2fe059a1098966d5ebf5b9
    Application ID               : {4dc3e181-e14b-4a21-b022-59fc669b0914}
    Certificate Store Name       : MY
    Verify Client Certificate Revocation : Enabled
    Verify Revocation Using Cached Client Certificate Only : Disabled
    Usage Check                  : Enabled
    Revocation Freshness Time    : 0
    URL Retrieval Timeout        : 0
    Ctl Identifier               : (null)
    Ctl Store Name               : (null)
    DS Mapper Usage              : Enabled
    Negotiate Client Certificate : Disabled

Also I'm not able to connect with PS:

VERBOSE: Connecting to BitServer.ad.bitprosinc.com.
New-PSSession : [bitserver.ad.bitprosinc.com] Connecting to remote server bitserver.ad.bitprosinc.com failed with the
following error message : [ClientAccessServer=BITSERVER,BackEndServer=bitserver.ad.bitprosinc.com,RequestId=5e4580a6-09
d1-42ac-adbd-e39fd22ded2b,TimeStamp=6/6/2015 8:15:09 PM]  For more information, see the about_Remote_Troubleshooting
Help topic.
At line:1 char:1
+ New-PSSession -ConnectionURI "$connectionUri" -ConfigurationName Microsoft.Excha ...
+ ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
    + CategoryInfo          : OpenError: (System.Manageme....RemoteRunspace:RemoteRunspace) [New-PSSession], PSRemotin
   gTransportException
    + FullyQualifiedErrorId : -2144108477,PSSessionOpenFailed
VERBOSE: Connecting to BitServer.ad.bitprosinc.com.
New-PSSession : [bitserver.ad.bitprosinc.com] Connecting to remote server bitserver.ad.bitprosinc.com failed with the
following error message : [ClientAccessServer=BITSERVER,BackEndServer=bitserver.ad.bitprosinc.com,RequestId=46c1c6c2-bc
b7-4705-8636-f036d4039c4e,TimeStamp=6/6/2015 8:15:12 PM]  For more information, see the about_Remote_Troubleshooting
Help topic.
At line:1 char:1
+ New-PSSession -ConnectionURI "$connectionUri" -ConfigurationName Microsoft.Excha ...
+ 

Hi dan,

Thank you for your question.

As you said that: I'm getting this error in my event viewer after mistakenly changing a binding to a SSL Cert in IIS. Could you tell me more details which SSL cert change?

Did you login on mailbox by OWA?

Did the outlook work correctly?

First of all, we should make sure Exchange 2013 CAS could ping domain controller and Exchange 2013 mailbox. Then restart IIS on Exchange CAS server to check if the issue persist.

If not, change Exchange virtual directory into default setting by the following link:

https://technet.microsoft.com/en-us/library/gg247612%28v=exchg.150%29.aspx

Notice: when we change IIS configuration, we should restart IIS to work.

Then check if there are any errors in application log and send those errors to ibsexc@microsoft.com for our troubleshooting.

If there are any questions regarding this issue, please be free to let me know.

Best Regard,

Jim