we have server 2008 r2 x64, exchange 2010 with Outlook 2010 x64 installed and have given Mailbox Import Export permissions to a user and get this error code -2147221220 We are trying to get Good Technologies going...not sure if anyone has experience with that.

It is my experience that Good requires full mailbox access right, not just mailbox import and export rights. You might want to check your documentation.Ed Crowley MVP "There are seldom good technological solutions to behavioral problems."

Okay, I've went in and enabled full control for the user for the mailbox via Management Console -> Mailbox -> Manage Full Access Permissions -> Add Added my user and that seemed fine, I restarted Exchange Information Store service, logged out and in on the computer I"m attempting this from and still no dice... Exact wording: SEVERE Unable to open Microsoft Exchange(R) session on profile 'GoodLink Server'. It may be due to invalid profile parameters, connection problems to the Exchange, replication delay, insufficient permissions to open the mailbox specified in the profile or the mailbox is over quota. Exchange system error:-2147221219, The Microsoft Exchange Server computer is not available. Either there are network problems or the Microsoft Exchange Server computer is down for maintenance.

I got it! Good Technologies tech support was quite helpful, and the problem was that I did not have a Public Folder Store created/mounted yet for the mailbox I was attempting to reach. Probably just a little of my Exchange newb-ness showing, but for anybody else having this issue, that fixed it for me. Thanks for the suggestion Ed!