Hi CrastalBea,
Based on your description, first I suggest you try to open this Excel file in safe mode, if it works fine please go to File- Excel Options- Add-Ins- select Com Add-ins- disable them.
And you can also copy the same file to other users' computers, and check if it works fine.
If this issue also occurs in other users' computers, please try to repair this file and check the data in your Excel file.
Open a blank Excel- go to Open option- Select the file- Click the arrow next to the Open button- Click Open and Repair.
If possible, I suggest you send this file to our email address and I will help you check this file:
ibsofc@microsoft.com
Please Note: Please add the URL of the case in the email subject or body.
If this issue only occurs in your own computer, please Go to Control Panel and repair Office.
Try these methods and let me know if they work for you.
I'm glad to help and follow up your reply.
Regards,
Emi Zhang
TechNet Community Su