I have windows 7 home premium and suddenly my mouse pad disable doesn't work?

Hi,

Please refer to the following article for some troubleshooting:

Mouse, touchpad, and keyboard problems in Windows

http://windows.microsoft.com/en-us/windows/help/mouse-touchpad-keyboard-problems-in-windows#v1h=tab01

Additionally, this forum focuses on general discussion about Exchange 2013. Since your issue is related to Windows 7, I suggest we can ask a question in Windows client forum for more help:

https://social.technet.microsoft.com/Forums/windows/en-Us/home?category=w7itpro

Regards,