We are having a hard time figuring this out. Server is 2008 R2, fully patched. Office 2010 Standard works fine, but if we try to use 2010 Pro, everything launches except for Word. When you launch Word, there is no splash screen, nothing happens. If you try again, it asks if you want to open in Safe Mode, this does nothing either.
Yet Excel, OneNote, Powerpoint all open with no issue.
We are using an MSP, but we did on Standard as well but didn't run into this issue. Nothing stands out in the Application log. I had patched Office as well.