We have migrated all of our users from Exchange 2003 to Exchange 2010.  Our Exchange 2003 servers are still powered up because we are not allowed to turn them off yet.  I have one user out 3500 that is having a problem with her out of office.  When she tries to open up the Out of Office Assistant she get the following message:"Your out office settings cannot be displayed because the server is currently unavailable".  She can set her Out of Office through OWA.  Here are some of things that I have tried to fix the issue:

1. User was using Office 2007 so I upgraded her to SP3

2. Installed Office 2010

3. Deleted Outlook profile

4. Deleted local user profile on her desktop

5. Moved mailbox to a different Database

I ran the Test E-mail configuration and got these results: (Autoconfiguration was unable to determine your settings!). I ran the same test from her computer using my email address and Autodiscover tested successfully.

I have two servers that have the HUB/CAS roles installed on them, the servers are clustered using NLB.  On these two servers the InternalNLBBypassUrls do not match, one has the FQDN and the other does not.  Does this matter?  Any ideas on what could be causing the problem for this user?

We have migrated all of our users from Exchange 2003 to Exchange 2010.  Our Exchange 2003 servers are still powered up because we are not allowed to turn them off yet.  I have one user out 3500 that is having a problem with her out of office.  When she tries to open up the Out of Office Assistant she get the following message:"Your out office settings cannot be displayed because the server is currently unavailable".  She can set her Out of Office through OWA.  Here are some of things that I have tried to fix the issue:

1. User was using Office 2007 so I upgraded her to SP3

2. Installed Office 2010

3. Deleted Outlook profile

4. Deleted local user profile on her desktop

5. Moved mailbox to a different Database

I ran the Test E-mail configuration and got these results: (Autoconfiguration was unable to determine your settings!). I ran the same test from her computer using my email address and Autodiscover tested successfully.

I have two servers that have the HUB/CAS roles installed on them, the servers are clustered using NLB.  On these two servers the InternalNLBBypassUrls do not match, one has the FQDN and the other does not.  Does this matter?  Any ideas on what could be causing the problem for this user?

Hello,

Please post the result from test e-mail autoconfiguration.

Here is the thread for your reference.

http://social.technet.microsoft.com/Forums/exchange/en-US/22a81d62-943b-4115-8df0-09f0babe218a/out-of-office-not-working-exchange-2010-migrated-from-exchange-2007

Please have a look at user's Internet Explorer configuration. Does she connect to Internet using some kind of proxy server? Is it possible that the local autoconfig URL not being bypassed and Internet Explorer tries to resolve internal autoconfiguration webaddress using external internet DNS?