When opening Excel attachments in Outlook 2010 (32 bit), Excel launches, but the file does not open, just a grey background.  We have tried the following:

- Disable all Add-ins (both in Outlook and Excel)

- Deleted all files from Outlook Secure Cache

- Disabled DDE

- Full remove and re-install

- Re-associated file types (.xls and .xlsx)

- Run ad Administrator and removed all COM Add-Ins

- Confirmed the following:HKEY_CLASSES_ROOT\Excel.Sheet.8\shell\Open\command

Specifically, Excel 2010 use (Default) Value Data:   "C:\Program Files\Microsoft Office\Office14\EXCEL.EXE" /dde

At this point I am out of solutions and find myself re-reading articles I have already seen.  I am about to buy a support incident, but wanted to exhaust all options here first.

Any suggestions are appreciated.

• Edited by Admin Paul Thursday, July 23, 2015 2:12 PM spelling

Hi Paul,

Based on your description, it seems that you have tried several methods to help you solve your issue. Does this occur when the attachment is saved locally?

I suggest you create a new profile in outlook, and test if this issue persist when opening Excel attachments.

About how to create a new profile, please refer to this KB article:
https://support.microsoft.com/en-us/kb/829918

Any updates please let me know, I'm glad to help and follow up your reply.

Regards,

Emi Zhang
TechNet Community Su