Does anyone have experience or thoughtsplanning and deploying SCCM 2007onServer 2008 in a very large enterprise across multiple ADforests to share?Assume native mode and established PKI structure.

Hi, I strongly recommend you to post the issue in SCCM forum to get relevant help. Here, Exchange Forum ,we may focus on Exchange related issue. Configuration Manager Setup/Deployment http://forums.microsoft.com/TechNet/ShowForum.aspx?ForumID=1821&SiteID=17 Related information share with you: Configuration Manager Multiple Site Planning and Deployment http://technet.microsoft.com/en-us/library/bb693854.aspx Thanks for your understanding. Hope it helps. Xiu