Hi,
Before this issue occurred, what did you perform in Outlook?
Based on the error message, it seems like a permission issue. Try to run Outlook as administrator, check if the issue persists.
Please also try to start Outlook in Safe Mode. Sometimes the 3rd-party add-ins will cause the Outlook startup issue, run Outlook in Safe Mode will disable these add-ins:
Press Win + R, type "outlook.exe /safe" in the blank box, press Enter.
If there is no issue starting Outlook in Safe Mode, consider to disable the suspicious add-ins from FILE -> Options -> Add-Ins.
If the issue still exists, please send me the image of the error message and let me know in detail the steps you performed before this issue occurred. To protect your private information, please send the image to our email address:
Regards,
Melon ChenTechNet Community Support