Outlook 2007 autocomplete runs slowly when typing in recipient addresses when Buffer Overflow protection is enabled https://kc.mcafee.com/corporate/index?page=content&id=KB50523 How to troubleshoot performance issues in Outlook 2007 http://support.microsoft.com/kb/940226 The only other suggestion is to check your print drivers they could be a factor as well in slow office performance. (remove all installed printers and try without them)