My sd slot not supporting sd cards. Is it hardware problem or something else?

Hi,

Check if the drivers are updated\detected in Device manager or not.

More often than not when a device isn't working it is because the driver has become corrupted. Re-installing a fresh copy should help http://windows.microsoft.com/en-us/windows7/Update-a-driver-for-hardware-that-isnt-working-properly?SignedIn=1
http://captaindbg.com/how-to-update-drivers-on-windows-7/   (works on win 8 & win 10)